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The government of India has banned certain combinations of medicines as being
non-rational and one among them is a fixed-dose combination of
dextropropoxyphene with any other drug other than anti-spasmodics and/ or
non-steroidal anti-inflammatory drugs (NSAIDs). I came across two formulations
being sold under brand names Spasmo Proxyvon and Buta-Proxyvon which contain
Acetaminophen/Paracetamol which is being, termed as an NSAID and my
investigation shows that acetaminophen is anti-pyretic and analgesic and not
NSAID. Thus, I feel these two brands belong in the banned category of
formulations and the medical fraternity should exercise utmost caution
prescribing this combination. According to the drugs controller for Karnataka,
acetaminophen is basically an anagesic/antipyretic, its anti-inflammatory
property is weak and seldom clinically useful and hence it cannot be classifed
as an anti-inflammatory drug under the category NSAID. Further, Indian
Pharmacopoeia 1996, an authentic reference published by the ministry of health
and family welfare, government of India, has classified it as an analgesic,
antipyretic, and not as NSAID. S Ramananda, Bangalore, Published in The Times of
India,Bangalore, September 1, 1999.
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